4,096 research outputs found
A systematic review of risk of HIV transmission through biting or spitting: implications for policy.
OBJECTIVES: The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of "spit hoods" by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmission as one justification. We aimed to review literature relating to the risk of HIV transmission through biting or spitting. METHODS: A systematic literature search was conducted using Medline, Embase and Northern Lights databases and conference websites using search terms relating to HIV, AIDS, bite, spit and saliva. Inclusion and exclusion criteria were applied to identified citations. We classified plausibility of HIV transmission as low, medium, high or confirmed based on pre-specified criteria. RESULTS: A total of 742 abstracts were reviewed, yielding 32 articles for full-text review and 13 case reports/series after inclusion and exclusion criteria had been applied. There were no reported cases of HIV transmission related to spitting and nine cases identified following a bite, in which the majority occurred between family (six of nine), in fights involving serious wounds (three of nine), or to untrained first-aiders placing fingers in the mouth of someone having a seizure (two of nine). Only four cases were classified as highly plausible or confirmed transmission. None related to emergency workers and none were in the UK. CONCLUSIONS: There is no risk of transmitting HIV through spitting, and the risk through biting is negligible. Post-exposure prophylaxis is not indicated after a bite in all but exceptional circumstances. Policies to protect emergency workers should be developed with this evidence in mind
Erupted cumulate fragments in rhyolites from Lipari (Aeolian Islands)
Over the last similar to 267 ky, the island of Lipari has erupted magmas ranging in compositions from basaltic andesites to rhyolites, with a notable compositional gap in the dacite field. Bulk geochemical and isotopic compositions of the volcanic succession, in conjunction with major and trace elemental compositions of minerals, indicate that the rhyolites were dominantly generated via crystal fractionation processes, with subordinate assimilation. Radiogenic (Sr, Nd, and Pb) and stable (O) isotopes independently suggest <= 30 % of crustal contamination with the majority of it occurring in mafic compositions, likely relatively deep in the system. Within the rhyolites, crystal-rich, K2O-rich enclaves are common. In contrast to previous interpretations, we suggest that these enclaves represent partial melting, remobilization and eruption of cumulate fragments left-over from rhyolite melt extraction. Cumulate melting and remobilization is supported by the presence of (1) resorbed, low-temperature minerals (biotite and sanidine), providing the potassic signature to these clasts, (2) reacted Fo-rich olivine, marking the presence of mafic recharge, (3) An(38-21) plagioclase, filling the gap in feldspar composition between the andesites and the rhyolites and (4) strong enrichment in Sr and Ba in plagioclase and sanidine, suggesting crystallization from a locally enriched melt. Based on Sr-melt partitioning, the high-Sr plagioclase would require similar to 2300 ppm Sr in the melt, a value far in excess of Sr contents in Lipari and Vulcano magmas (50-1532 ppm) but consistent with melting of a feldspar-rich cumulate. Due to the presence of similar crystal-rich enclaves within the rhyolites from Vulcano, we propose that the eruption of remobilized cumulates associated with high-SiO2 rhyolites may be a common process at the Aeolian volcanoes, as already attested for a variety of volcanic systems around the world
Applying the 3C Model to FLOSS communities
Publicado em "Collaboration and technology: 22nd International Conference, CRIWG 2016, Kanazawa, Japan, September 14-16, 2016, proceedings". ISBN 978-3-319-44798-8How learning occurs within Free/Libre Open Source (FLOSS)
communities and what is the dynamics such projects (e.g. the life cycle
of such projects) are very relevant questions when considering the use of
FLOSS projects in a formal education setting. This paper introduces an
approach based on the 3C collaboration model (communication, coordination
and cooperation) to represent the collaborative learning dynamics
within FLOSS communities. To explore the collaborative learning potential
of FLOSS communities a number of questionnaires and interviews
to selected FLOSS contributors were run. From this study a 3C collaborative
model applicable to FLOSS communities was designed and
discussed.Programa Operacional da Região Norte, NORTE2020, in the context of project NORTE-01-0145-FEDER-000037FCT under grant SFRH/BSAB/113890/201
A Geometric Approach to CP Violation: Applications to the MCPMFV SUSY Model
We analyze the constraints imposed by experimental upper limits on electric
dipole moments (EDMs) within the Maximally CP- and Minimally Flavour-Violating
(MCPMFV) version of the MSSM. Since the MCPMFV scenario has 6 non-standard
CP-violating phases, in addition to the CP-odd QCD vacuum phase \theta_QCD,
cancellations may occur among the CP-violating contributions to the three
measured EDMs, those of the Thallium, neutron and Mercury, leaving open the
possibility of relatively large values of the other CP-violating observables.
We develop a novel geometric method that uses the small-phase approximation as
a starting point, takes the existing EDM constraints into account, and enables
us to find maximal values of other CP-violating observables, such as the EDMs
of the Deuteron and muon, the CP-violating asymmetry in b --> s \gamma decay,
and the B_s mixing phase. We apply this geometric method to provide upper
limits on these observables within specific benchmark supersymmetric scenarios,
including extensions that allow for a non-zero \theta_QCD.Comment: 34 pages, 16 eps figures, to appear in JHE
Detecting temporal and spatial effects of epithelial cancers with Raman spectroscopy.
PublishedJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tThis is the final version of the article. Available from Hindawi Publishing Corporation via the DOI in this record.Epithelial cancers, including those of the skin and cervix, are the most common type of cancers in humans. Many recent studies have attempted to use Raman spectroscopy to diagnose these cancers. In this paper, Raman spectral markers related to the temporal and spatial effects of cervical and skin cancers are examined through four separate but related studies. Results from a clinical cervix study show that previous disease has a significant effect on the Raman signatures of the cervix, which allow for near 100% classification for discriminating previous disease versus a true normal. A Raman microspectroscopy study showed that Raman can detect changes due to adjacent regions of dysplasia or HPV that cannot be detected histologically, while a clinical skin study showed that Raman spectra may be detecting malignancy associated changes in tissues surrounding nonmelanoma skin cancers. Finally, results of an organotypic raft culture study provided support for both the skin and the in vitro cervix results. These studies add to the growing body of evidence that optical spectroscopy, in this case Raman spectral markers, can be used to detect subtle temporal and spatial effects in tissue near cancerous sites that go otherwise undetected by conventional histology.The authors acknowledge the financial support of the
NCI/NIH (R01-CA95405 and R21-CA95995), as well
as the Howard Hughes Medical Institute (pre-doctoral
fellowship for MK). We would also like to thank the
doctors and staff at Vanderbilt University Medical Center
and Tri-state Women’s Health for all their assistance
Business process modelling and visualisation to support e-government decision making: Business/IS alignment
© 2017 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/978-3-319-57487-5_4.Alignment between business and information systems plays a vital role in the formation of dependent relationships between different departments in a government organization and the process of alignment can be improved by developing an information system (IS) according to the stakeholders’ expectations. However, establishing strong alignment in the context of the eGovernment environment can be difficult. It is widely accepted that business processes in the government environment plays a pivotal role in capturing the details of IS requirements. This paper presents a method of business process modelling through UML which can help to visualise and capture the IS requirements for the system development. A series of UML models have been developed and discussed. A case study on patient visits to a healthcare clinic in the context of eGovernment has been used to validate the models
CP Violation in Supersymmetry with Effective Minimal Flavour Violation
We analyze CP violation in supersymmetry with Effective Minimal Flavour
Violation, as recently proposed in arXiv:1011.0730. Unlike the case of standard
Minimal Flavour Violation, we show that all the phases allowed by the flavour
symmetry can be sizable without violating existing Electric Dipole Moment
constraints, thus solving the SUSY CP problem. The EDMs at one and two loops
are precisely analyzed as well as their correlations with the expected CP
asymmetries in B physics.Comment: 22 pages, 7 figures. v2: Discussion in section 2 extended,
conclusions unchanged. Matches published versio
CP violation in sbottom decays
We study CP asymmetries in two-body decays of bottom squarks into charginos
and tops. These asymmetries probe the SUSY CP phases of the sbottom and the
chargino sector in the Minimal Supersymmetric Standard Model. We identify the
MSSM parameter space where the CP asymmetries are sizeable, and analyze the
feasibility of their observation at the LHC. As a result, potentially
detectable CP asymmetries in sbottom decays are found, which motivates further
detailed experimental studies for probing the SUSY CP phases.Comment: 29 pages, 7 figure
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